Esketamine
Nasal NMDA antagonist antidepressant
Episodes
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#3524: The Glutamate Trap: Hangovers, Panic, and the BrainWhy alcohol, caffeine, and poor sleep create a perfect neurochemical storm — and what it reveals about anxiety. -
#3521: SSRIs: How Different Are They Really?Prozac, Lexapro, and beyond — how similar are SSRIs? A deep dive into selectivity, side effects, and what comes next. -
#3239: Why the Brain Doesn't Fight Back Against VyvanseHow SSRIs and Vyvanse trick the brain’s homeostatic machinery into healing instead of resisting. -
#2529: Depression Subtypes: Is It Cognitive or Biological?Not all depression is the same. Here's what science says about melancholic, atypical, and biotype-based subtypes.