Seroquel
Antipsychotic used off-label for sleep
Episodes
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#5186: Why the Last Milligrams Are the HardestMost drugs come in doses designed for stable use — not for the tiny steps safe withdrawal requires. Here's what's changing. -
#3070: The Hidden World of Custom Drug DosingWhy getting a precise 6.25mg Seroquel dose reveals the strange economics of custom medicine. -
#2663: When Opposing Drugs CooperateTwo opposing drugs collide in your system. Do they cancel out or work together? -
#2619: The Sleep Doctor ShortageNight owls vs. clinical disorder—what sleep medicine actually says about delayed sleep-wake phase. -
#2589: Can You Actually See a Sleep Specialist?Sleep medicine is real but hard to access. Here’s how the system works and what actually helps. -
#2528: How New Drugs Actually Fix Your Body ClockMelatonin receptor agonists vs. sedatives — the science of fixing your clock instead of knocking it out. -
#1588: The Architecture of Sleep: Rebuilding Restorative RestIs sedation the same as sleep? Explore the biological map of rest and learn how to renovate your brain’s nightly cycles for true recovery. -
#1192: Why You’re Taking 100x More Melatonin Than You NeedFrom gas station gummies to prescription drugs, we dive into the "melatonin paradox" and why your 10mg dose might be a "flamethrower." -
#976: From Monkey Jaws to Sleep Apnea: A Career PivotDiscover how years of primate research paved the way for modern sleep apnea treatments and a new era of dental sleep medicine. -
#840: Why Antidepressants Take Weeks to Work: The Science of LagSSRIs change brain chemistry in hours, but mood lifts weeks later. Explore the "construction project" and neuroplasticity behind the wait. -
#690: One Size Fits None: The Future of Precision MedicineWhy do we all take the same pill dose? Explore how genetics and 3D printing are ending the era of "one size fits all" pharmacology. -
#540: Sedation vs. Sleep: The Science of Restorative RestAre sleep meds helping or just knocking you out? Explore the gap between chemical sedation and true restorative sleep in this deep dive. -
#445: Beyond the Pill: The Science of Tapering Sleep MedsHerman and Corn explore the science of tapering sleep meds, the "histamine rebound," and how to reclaim your natural rest.