Prucalopride
Peripheral prokinetic for gut motility
Episodes
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#5695: Gut-Brain Drugs: Why Old Antidepressants Help BloatingA listener with post-cholecystectomy bloating asks why an old antidepressant might help — and whether anything better is coming. -
#5694: Prokinetics When the Emptying Test Is NormalA negative gastric emptying study doesn't close the door on prokinetics — because the drugs may not work the way we assumed. -
#3525: Can Drugs Target the Gut Without Fogging the Brain?Why amitriptyline knocks you out—and what's being designed to avoid that. -
#3401: How UDCA Fixes Your Bile Chemistry (Not the Reflux)UDCA doesn't stop bile reflux—it swaps harsh bile acids for gentle ones, protecting your stomach lining. -
#3354: Bile Reflux After Gallbladder Removal: What WorksBile reflux after gallbladder removal affects up to 110,000 new patients yearly. No FDA-approved drug exists. Here's what helps. -
#2583: The Motility Blind SpotWhy bile moves backward after gallbladder removal—and what treatments actually address the mechanical problem.