Metoclopramide

A listener with post-cholecystectomy bloating asks why an old antidepressant might help — and whether anything better is coming.

A negative gastric emptying study doesn't close the door on prokinetics — because the drugs may not work the way we assumed.

One in five antipsychotic patients develops TD. Why does it stick around after the drug stops — and how much do newer drugs help?

Dopamine blockers stop nausea but cause brutal next-day fatigue. Why the same receptor does both — and what makes them risky long-term.

UDCA doesn't stop bile reflux—it swaps harsh bile acids for gentle ones, protecting your stomach lining.

Why bile moves backward after gallbladder removal—and what treatments actually address the mechanical problem.

The stomach isn't passive—it actively relaxes to hold food. Here’s what happens when that reflex breaks.