Chlorpromazine
First antipsychotic, introduced mid-1950s
Episodes
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#5920: The Psychiatrist in Those 1950s Patient FilmsA drug salesman's papers, a bathtub, and the 1950s interviews with Dr. Heinz Edgar Lehmann that still pull millions of views. -
#5474: Why Tardive Dyskinesia Becomes PermanentOne in five antipsychotic patients develops TD. Why does it stick around after the drug stops — and how much do newer drugs help? -
#3239: Why the Brain Doesn't Fight Back Against VyvanseHow SSRIs and Vyvanse trick the brain’s homeostatic machinery into healing instead of resisting.